INNOVATION

The first application of the Claros technology is a system to perform quantitative immunoassay blood tests. Immunoassays, which are primarily used to detect proteins, make up the largest family of in-vitro diagnostics and include tests for infectious diseases, cancer, and immune diseases, among many others. Due to their complexity, the majority of these tests can only be performed in large laboratories with expensive equipment and trained scientists, limiting their use to hospital settings with laboratory access and requiring extensive periods of time (often days) for results. The proprietary Claros technologies, originally developed by the founders of Claros in the Harvard University laboratory of Professor George Whitesides, enable inexpensive, portable, and simple-to-use quantitative laboratory-quality immunoassays. The ease-of-use associated with our technology will result in a system that can be used by anyone, anywhere. Claros has incorporated its proprietary detection, fluid handling, and manufacturing technologies into a diagnostic system encompassing a disposable test cartridge and a point-of-care analyzer.

Disposable Cartridge
Cartridge
  • A single credit card sized cartridge can yield quantitative results for multiple markers simultaneously.
  • Requires only a finger-stick of whole blood.
  • Capability for quantitative analysis of blood, serum, urine, and other bodily fluids.
Analyzer
Analyzer
  • Can be packaged as a bench-top instrument or battery-operated hand-held unit.
  • No sample preparation or user intervention.
  • Intelligent QC (monitor each assay step to guarantee result accuracy).
  • Results are available in less than 15 minutes.
  • Wireless, wired, or printer output capable.

Analyzers shown:

Top Image: The Claros benchtop analyzer for use in physician offices.

Bottom Image: A handheld, battery-operated analyzer, developed in collaboration led by Professor Samuel Sia (Columbia University, Pratt School of Art & Design, Smart Design, and Claros) specifically for field use in low-resource settings globally.